Scientific Opinion on the Use of Non-human Primate Models for Human Tses Adopted by the Scientific Steering Committee
ثبت نشده
چکیده
In the light of the background report presented in section II, the Scientific Steering Committee considers that studies in non-human primates should make an important and unique contribution to several experiments aimed at quantifying TSE associated risks in humans. They will also contribute important and valuable information to the pre-clinical development of new therapeutic strategies and validation of diagnostic tools. Lemurs, macaques and squirrel monkeys are susceptible to TSE agent infection, and their infection constitutes a valuable scientific and relevant model of human TSEs. In the current stage of the knowledge, apart from future vaccine strategy evaluation, chimpanzees need not to be used in TSE research.
منابع مشابه
The SCHER report on non-human primate research - biased and deeply flawed.
The European Commission's Scientific Committee on Health and Environmental Risks (SCHER) recently issued an Opinion on the need for non-human primate (NHP) use in biomedical research, and the possibilities of replacing NHP use with alternatives, as part of the Directive 86/609/EEC revision process. Here, we summarise our recent complaint to the European Ombudsman about SCHER's Opinion and the e...
متن کاملScientific Opinion on Stunning Methods and Bse Risks (the Risk of Dissemination of Brain Particles into the Blood and Carcass When Applying Certain Stunning Methods.) Adopted by the Scientific Steering Committee
متن کامل
P-50: Elongating and Elongated Spermatids Manufactured In Vitro from Non-Human Primate Pluripotent Stem Cells
Background: We have recently shown that human embryonic (hESCs) and induced pluripotent stem cells (hiPSCs) can differentiate into advanced spermatogenic cells including round spermatids by in vitro culture (Easley et al., Direct differentiation of human pluripotent stem cells into haploid spermatogenic cells. Cell Reports 2, 440-446 2012) and also, in collaboration, that rhesus spermatogonial ...
متن کاملShort-latency category specific neural responses to human faces in macaque inferotemporal cortex
In this article I would present evidence to show that timing of the flow of neural signals within the ventral visual stream is a crucial part of the neural code for categorization of faces. We recorded the activity of 554 inferotemporal neurons from two macaque monkeys performing a fixation task. More than 1000 object images including human and non-primate animal faces were presented up to 10 t...
متن کاملResponse to Some Biosafety Concerns of Transgenic Plants
Plant genetic engineering has been the fastest technology adopted in human history to achieve quantitative and qualitative superiority by farmers. This technology has real benefits to the environment and the livelihood of farmers. Unfortunately, despite numerous credible scientific studies on the safety of GM products for the consumer and the environment, this technology still faces misleading ...
متن کامل